منابع مشابه
A clarification of the Hardy-Weinberg law.
C. C. Li showed that Hardy-Weinberg proportions (HWP) can be maintained in a large population by nonrandom mating as well as random mating. In particular he gave the mating matrix for the symmetric case in the most general form possible. Thus Li showed that, once HWP are attained, the same proportions can be maintained by what he called pseudorandom mating. This article shows that, starting fro...
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Under random mating, a progeny's alleles are independently sampled from the parental gene pools. Here is a new proof which avoids the usual algebraic complexity, based on a restated Mendel's First Law. Another simplified proof along the old approach led to the discovery that allelic independence can hold under random mating and fertility selection. The theoretical existence and number of such s...
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THE Hardy-Weinberg law is the cornerstone of dipalso, even more crucial, that Mendelism and Darwin’s loid population genetics. Yet it seems trivially obviidea of continuous evolution were compatible” (Proous, a routine application of the binomial theorem. And vine 1971, p. 85). Yule’s statement was a curious slip indeed it was so regarded by Hardy when he wrote his for a man who had introduced ...
متن کاملBayesian methods for examining Hardy-Weinberg equilibrium.
Testing for Hardy-Weinberg equilibrium is ubiquitous and has traditionally been carried out via frequentist approaches. However, the discreteness of the sample space means that uniformity of p-values under the null cannot be assumed, with enumeration of all possible counts, conditional on the minor allele count, offering a computationally expensive way of p-value calibration. In addition, the i...
متن کاملExact tests for Hardy-Weinberg proportions.
Exact conditional tests are often required to evaluate statistically whether a sample of diploids comes from a population with Hardy-Weinberg proportions or to confirm the accuracy of genotype assignments. This requirement is especially common when the sample includes multiple alleles and sparse data, thus rendering asymptotic methods, such as the common chi(2)-test, unreliable. Such an exact t...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2005
ISSN: 1415-4757
DOI: 10.1590/s1415-47572005000300027